Paul Bevan

POTENTIATION BY DESIPRAMINE OF NEURONAL RESPONSES TO MESCALINE

British Journal of Pharmacology May 1, 1976 Paul Bevan, C. M. Bradshaw, E. Szabadi 4 citations

The effect of desipramine on responses of single cortical neurones to mescaline was studied by the microelectrophoretic technique. Both potentiation and antagonism of responses to mescaline by desipramine were observed. The antagonism may be related to the α‐adrenolytic action of desipramine. The potentiation is unlikely to reflect the uptake blocking action of desipramine, since desipramine...