THE UPTAKE AND DISTRIBUTION OF 14C-MESCALINE IN DIFFERENT ORGANS OF DEVELOPING RAT
Drug Metabolism and Disposition March 1, 1975 Nandkumar S. Shah, Kanhaiya R. Shah, R.s. Lawrence et al. 6 citations
Rats of 1,4,8,12,20, and 60 days postnatal age were injected ip with 14-C-mescaline (50 nCi/g). The levels of mescaline and its deaminated metabolite, 3,4,5-trimethoxyphenylacetic acid, were examined in the brain, liver, heart, spleen, lung, and kidney at 30, 60, 90, and 120 min. Mescaline was rapidly taken up by all the organs examined. In general, the organs of younger rats accumulated much...