Cheryl M Collins

Parallel changes in serotonin levels in brain and blood following acute administration of MDMA

Journal of Psychopharmacology October 10, 2012 Cheryl M Collins, Joris Kloek, J.m. Elliott 28 citations

Recent studies have demonstrated a similar acute effect of 3,4- methylenedioxymethamphetamine (MDMA) in blood platelets and brain tissue via action on the serotonin transporter. To investigate the validity of blood serotonin as a peripheral marker for central serotonin in this regard, we administered MDMA (20 mg/kg i.p.) to rats and observed a parallel decrease in serotonin levels in the...