Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals
Science September 6, 1985 George A. Ricaurte, Guy K. Bryan, L. Strauss et al. 367 citations
(±)-3,4-Methylenedioxyamphetamine (MDA), an amphetamine analog with hallucinogenic activity, produced selective long-lasting reductions in the level of serotonin, the number of serotonin uptake sites, and the concentration of 5-hydroxyindoleacetic acid in rat brain. Morphological studies suggested that these neurochemical deficits were due to serotonin nerve terminal degeneration. These results...