Examining the role of oxytocin in the interoceptive effects of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) using a drug discrimination paradigm in the rat
Addiction Biology November 11, 2010 Jillian H. Broadbear, Brendan J. Tunstall, Katherine Beringer 38 citations
ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA, ‘ecstasy’) use results in distinctive mood changes of a prosocial nature, most likely through its enhancement of serotonin (5HT) neurotransmission. Activation of 5HT‐1A postsynaptic receptors has been shown to stimulate the release of oxytocin in the central nervous system where it regulates aspects of mood and behavior. Using a drug...