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Jadwiga Wardas

2 papers in the library · 52 citations · publishing 2013-2017

Papers

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Widespread reduction of dopamine cell bodies and terminals in adult rats exposed to a low dose regimen of MDMA during adolescence.

Neuropharmacology September 1, 2017 Cristina Cadoni, Augusta Pisanu, Nicola Simola et al.

Although MDMA (3,4-methylendioxymethamphetamine, ecstasy) neurotoxicity in serotonin neurons is largely recognized in a wide variety of species including man, neurotoxicity in dopamine (DA) neurons is thought to be species-specific. MDMA is mainly consumed by adolescents, often in conjunction with caffeine (Energy Drinks) and this association has been reported to exacerbate MDMA toxic effects....

DOI: 10.1016/j.neuropharm.2017.06.008 (opens in new tab) Full text (opens in new tab) MDMA 3,4-methylendioxymethamphetamine pubchem cid Caffeine pubchem cid Neurotoxicity +4

MPTP‐induced dopamine neuron degeneration and glia activation is potentiated in MDMA‐pretreated mice

Movement Disorders September 20, 2013 Giulia Costa, Lucia Frau, Jadwiga Wardas et al. 52 citations

ABSTRACT Clinical observations report a greater propensity to develop Parkinson's disease (PD) in amphetamine users. 3,4‐Methylenedioxymethamphetamine (MDMA; “ecstasy”) is an amphetamine‐related drug that is largely consumed by adolescents and young adults, which may have neuroinflammatory and neurotoxic effects. Here, the objective was to evaluate in mice whether consumption of MDMA during...

DOI: 10.1002/mds.25646 (opens in new tab) MDMA Mptp Dopamine Neuronal degeneration +2