Skip to content

Mark Grande

1 paper in the library · 50 citations · publishing 2004

Papers

Sort Most recent Most cited

Neurotoxic effects of MDMA (“ecstasy”) administration to neonatal rats

International Journal of Developmental Neuroscience June 5, 2004 Jerrold S. Meyer, Mark Grande, Kenneth M. Johnson et al. 50 citations

Abstract 3,4‐Methylenedioxymethamphetamine damages fine serotonergic fibers and nerve terminals in adult organisms. Developing animals seem to be less susceptible to this effect, possibly due to a lack of drug‐induced hyperthermia. We tested this hypothesis by producing hyperthermia in neonatal rats for 2 h after each of twice‐daily MDMA (10 mg/kg s.c.) or saline injections administered from...