Neurotoxic effects of MDMA (“ecstasy”) administration to neonatal rats
International Journal of Developmental Neuroscience June 5, 2004 Jerrold S. Meyer, Mark Grande, Kenneth M Johnson et al. 50 citations
Abstract 3,4‐Methylenedioxymethamphetamine damages fine serotonergic fibers and nerve terminals in adult organisms. Developing animals seem to be less susceptible to this effect, possibly due to a lack of drug‐induced hyperthermia. We tested this hypothesis by producing hyperthermia in neonatal rats for 2 h after each of twice‐daily MDMA (10 mg/kg s.c.) or saline injections administered from...
DOI: 10.1016/j.ijdevneu.2004.04.007 (opens in new tab)
MDMA
Serotonergic
Forebrain
Endocrinology
+4