Distinct neural mechanisms for the prosocial and rewarding properties of MDMA
Science Translational Medicine December 11, 2019 Boris D. Heifets, Juliana S Salgado, Madison Taylor et al. 119 citations
-fenfluramine, a selective serotonin-releasing compound. By dissociating the mechanisms of MDMA's prosocial effects from its addictive properties, we provide evidence for a conserved neuronal pathway, which can be leveraged to develop novel therapeutics with limited abuse liability.
DOI: 10.1126/scitranslmed.aaw6435 (opens in new tab)
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MDMA
Prosocial behavior
Pharmacology