Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user
Neurology July 25, 2000 Stephen J. Kish, Yoshiaki Furukawa, Lee-Cyn Ang et al. 119 citations
The authors found that striatal levels of serotonin and those of its metabolite 5-hydroxyindoleacetic acid were severely depleted by 50 to 80% in brain of a chronic user of methylenedioxymethamphetamine (MDMA) whereas concentrations of dopamine were within the normal control range. Our data suggest that MDMA exposure in the human can cause decreased tissue stores of serotonin and therefore some...