Journal of Psychopharmacology
March 1, 2006
Rainer Thomasius, P. Zapletalova, Kay Uwe Petersen et al.
158 citations
Although 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is a known serotonergic neurotoxin in different animal species, there is to date no conclusive evidence of its neurotoxicity in humans. MDMA use was associated with impairments of psychological well-being, verbal memory and altered serotonergic functioning in a number of crosssectional studies. Due to inherent methodological...
Addiction
July 15, 2005
Rainer Thomasius, Kay Uwe Petersen, P. Zapletalova et al.
54 citations
ABSTRACT Background Ecstasy use has often been found to be associated with psychopathology, yet this research has so far been based largely on subjective symptom ratings. Aims To investigate whether ecstasy users suffered from long‐term psychopathological consequences. Measurements We compared the prevalence of Diagnostic and Statistical Manual version IV (DSM‐IV) mental disorders in 30 current...
American Journal of Psychiatry
July 1, 2004
Ralph Buchert, Rainer Thomasius, Florian Wilke et al.
183 citations
These findings support the hypothesis of MDMA-induced protracted alterations of the serotonergic system and indicate that the reduced availability of serotonin transporter, as measured by PET, might be reversible. Women appear to be more susceptible than men to MDMA-induced alterations of the serotonergic system.
Fortschritte der Neurologie · Psychiatrie
February 1, 1997
Rainer Thomasius, Margit Schmolke, Dana Kraus
Epidemiological research and Substance Abuse Warning Systems point to a sharp increase in the use of "Ecstasy" (MDMA), as well as to structural changes in the drug scene in and outside Europe. For some consumers, "Ecstasy" opens the door to the abuse of other illegal substances. Since the mid-eighties psychiatric complications and consequences of the abuse of MDMA have been reported in at least...