This article reviews recent surveys and reports that provide insight regarding prevalence, frequency, trends, perceptions, and seizures of methylenedioxymethamphetamine (MDMA) or "Ecstasy." An estimated 6.4 million individuals have used MDMA. Among students in the eighth, 10th, and 12th grades, MDMA use has substantially increased from mid-1990 levels to 2001, with sharp increases noted in 2000...