Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats
Neurotoxicity Research April 15, 2019 Monika Herian, Adam Wojtas, Katarzyna Kamińska et al. 44 citations
NBOMes are N-benzylmethoxy derivatives of the 2C family hallucinogens. 4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe) is one of the commonly used illicit drugs. It exhibits high binding affinity for 5-HT 2A/C and 5-HT 1A serotonin receptors. Activation of 5-HT 2A receptor induces head-twitch response (HTR) in rodents, a behavioral marker of hallucinogen effect in humans....
DOI: 10.1007/s12640-019-00033-x (opens in new tab)
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Serotonin
Lysergic acid diethylamide
Hallucinogen
Neurochemical
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