Proteomic changes induced by harmine in human brain organoids reveal signaling pathways related to neuroprotection
bioRxiv (Cold Spring Harbor Laboratory) June 17, 2021 Karina Karmirian, Livia Goto-Silva, Juliana Nascimento et al. 1 citation preprint
Abstract Harmine is a β-carboline found in Banisteriopsis caapi , a constituent of ayahuasca brew. Ayahuasca is consumed as a beverage in native Americans’ sacred rituals and in religious ceremonies in Brazil. Throughout the years, the beneficial effects of ayahuasca to improve mental health and life quality have been reported, which propelled the investigation of its therapeutic potential to...