Psychedelics show promise in addressing infertility linked to obesity and insulin resistance. In a study of 150 women with polycystic ovary syndrome, 65% experienced improved ovulation rates after psychedelic therapy, alongside significant reductions in hyperinsulinemia and beneficial changes in adipokine levels. These findings suggest that psychedelics may influence neurotransmitter receptors, potentially aiding the endocrine system's regulation of hormones related to reproductive health. The implications extend to internal medicine and biophysics, highlighting a novel intersection between mental health and metabolic disorders.
Mindfulness, as deployed in contemporary psychology, increasingly functions as a cultural–psychological boundary object whose definition is shaped by outcome-based criteria, while its original ethical orientation, investigative function, and liberation-oriented purpose from early Buddhist frameworks recede. This conceptual analysis traces how assumptions about attention, embodiment, and purpose influence construct formation and validation, drawing on early Buddhist sources, historical analyses of Buddhist modernism, psychological measurement research, and studies of XR-based mindfulness interventions. The paper advocates for a pluri-epistemic approach to psychological science that foregrounds epistemic lineage and construct transparency, clarifying the trade-offs involved in abstraction, measurement, and scalability.