Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine
bioRxiv (Cold Spring Harbor Laboratory) February 13, 2017 Vanja Dakic, Juliana Nascimento, Rafaela Sartore et al. preprint
Abstract Dimethyltryptamines are hallucinogenic serotonin-like molecules present in traditional Amerindian medicine (e.g. Ayahuasca) recently associated with cognitive gains, antidepressant effects and changes in brain areas related to attention. Historical and technical restrictions impaired understanding how such substances impact human brain metabolism. Here we used shotgun mass spectrometry...