Structural Features for Functional Selectivity at Serotonin Receptors
Science March 21, 2013 Daniel Wacker, Chong Wang, Vsevolod Katritch et al. 689 citations
Dissecting Serotonin Receptors Serotonin receptors are the targets for many widely used drugs prescribed to treat ailments from depression to obesity and migraine headaches (see the Perspective by Palczewski and Kiser ). C. Wang et al. (p. 610 , published online 21 March) and Wacker et al. (p. 615 , published online 21 March) describe crystal structures of two members of the serotonin family of...