Interaction between LSD and dopamine D2/3 binding sites in pig brain
Synapse 2005 Luciano Minuzzi, George G. Nomikos, Mark Wade et al. 25 citations
The psychoactive properties of the hallucinogen LSD have frequently been attributed to high affinity interactions with serotonin 5HT2 receptors in brain. Possible effects of LSD on dopamine D2/3 receptor availability have not previously been investigated in living brain. Therefore, we used PET to map the binding potential (pB) of [11C]raclopride in brain of three pigs, first in a baseline...