Alan R. King

REVERSAL LEARNING ENHANCED BY LYSERGIC ACID DIETHYLAMIDE (LSD): CONCOMITANT RISE IN BRAIN 5‐HYDROXYTRYPTAMINE LEVELS

British Journal of Pharmacology November 1, 1974 Alan R. King, Ian L. Martin, Kathleen Melville 38 citations

Small doses of lysergic acid diethylamide (LSD) (12.5–50 μg/kg) consistently facilitated learning of a brightness discrimination reversal. 2‐Bromo‐lysergic acid diethylamide (BOL‐148), a structural analogue of LSD, with similar peripheral anti‐5‐hydroxytrypamine activity but no psychotomimetic properties, had no effect in this learning situation at a similar dose (25 μg/kg). LSD, but not...