Long-lasting alterations in 5-HT2A receptor after a binge regimen of methamphetamine in mice
The International Journal of Neuropsychopharmacology April 24, 2014 Hong‐yi Chiu, Ming‐huan Chan, Mei-Yi Lee et al. 31 citations
The repeated administration of methamphetamine (MA) to animals in a single-day 'binge' dosing regimen produces damage to dopamine and serotonin terminals and psychosis-like behaviours similar to those observed in MA abusers. The present study aimed to examine the effects of MA binge exposure on 5-HT2A receptors, the subtype of serotonin receptors putatively involved in psychosis. ICR male mice...
DOI: 10.1017/s1461145714000455 (opens in new tab)
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Serotonin
Prefrontal cortex
Methamphetamine
Agonist
+2