Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801.
Pharmacology, Biochemistry, and Behavior December 2018 Peter U Hámor, Jana Šírová, Tomáš Páleníček et al.
Chronic methamphetamine (meth) abuse often turns into a compulsive drug-taking disorder accompanied by persistent cognitive deficits and re-occurring psychosis. Possible common neurobiological substrates underlying meth-induced deficits and schizophrenia remain poorly understood. Serotonin 2A (5-HT2A) and metabotropic glutamate 2 (mGlu2) receptors co-regulate psychosis-like behaviors and...
DOI: 10.1016/j.pbb.2018.09.007 (opens in new tab)
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5-ht2a
Heterocomplex
Mk-801
Methamphetamine
+2