Psilocybin as a fast-acting and long-lasting antidepressant for adolescence: Proposing NeuroD1 as a biomarker of its long-term plasticity
Biomedicine & Pharmacotherapy October 30, 2025 Rubén García‐cabrerizo, Itziar Beruete-Fresnillo, Pedro Bergas-Cladera et al. 3 citations
Adolescent depression is a significant public health concern, yet treatment options remain limited, particularly due to age- and sex-related differences in antidepressant efficacy. This study explored for the first time the potential antidepressant-like response of psilocybin in adolescence by examining acute, repeated and persistent effects in Sprague-Dawley rats of both sexes, as measured...