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Stephanie E. Simonds

2 papers in the library · publishing 2025-2026

Papers

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Effects of a single dose of psilocybin on diet-induced weight loss in obese mice.

Translational Psychiatry April 14, 2026 Ryan J. Keenan, Rifa T Haque, Xiangjun Jin et al.

Prolonged obesity induces enduring structural changes within neural circuits that contribute to maintaining the body at an elevated/obese body weight. These circuits regulate various mechanisms which can inhibit extreme or persistent weight loss. Therefore, a potential therapeutic strategy to facilitate weight loss is to promote structural plasticity within the brain. Psychedelic compounds,...

Effects of a single dose of psilocybin on diet-induced weight loss in obese mice

March 31, 2025 Ryan J. Keenan, Rezaul Haque, Xianbo Jin et al.

Abstract Prolonged obesity induces enduring structural changes within neural circuits that contribute to maintaining the body at an elevated/obese body weight. These circuits regulate various mechanisms which can inhibit extreme or persistent weight loss. Therefore, a potential therapeutic strategy to facilitate weight loss is to promote structural plasticity within the brain. Psychedelic...