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Xianbo Jin

1 paper in the library · publishing 2025

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Effects of a single dose of psilocybin on diet-induced weight loss in obese mice

March 31, 2025 Ryan J. Keenan, Rezaul Haque, Xianbo Jin et al.

Abstract Prolonged obesity induces enduring structural changes within neural circuits that contribute to maintaining the body at an elevated/obese body weight. These circuits regulate various mechanisms which can inhibit extreme or persistent weight loss. Therefore, a potential therapeutic strategy to facilitate weight loss is to promote structural plasticity within the brain. Psychedelic...