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John J. Worthington

2 papers in the library · publishing 2013-2025

Papers

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Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus

Journal of Psychopharmacology April 17, 2025 Artur Pałasz, Marta Pukowiec, Katarzyna Bogus et al.

Objective: Psychedelics are able to trigger highly intense and profound alterations in self-consciousness, perception, affective, and cognitive processes. Indeed, recent studies show that ketamine and psilocybin could be used as fast-acting antidepressants. However, the molecular and neurochemical mechanisms of these psychedelics and their actions at the level of diverse brain structures...

Randomized Controlled Trial of Mindfulness Meditation for Generalized Anxiety Disorder: Effects on Anxiety and Stress Reactivity

The Journal of Clinical Psychiatry March 13, 2013 Elizabeth A Hoge, Eric Bui, L. Marques et al.

Objective Mindfulness meditation has met increasing interest as a therapeutic strategy for anxiety disorders, but prior studies have been limited by methodological concerns, including a lack of an active comparison group. This is the first randomized, controlled trial comparing the manualized Mindfulness-Based Stress Reduction (MBSR) program with an active control for Generalized Anxiety...