Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus
Journal of Psychopharmacology April 17, 2025 Artur Pałasz, Marta Pukowiec, Katarzyna Bogus et al.
Objective: Psychedelics are able to trigger highly intense and profound alterations in self-consciousness, perception, affective, and cognitive processes. Indeed, recent studies show that ketamine and psilocybin could be used as fast-acting antidepressants. However, the molecular and neurochemical mechanisms of these psychedelics and their actions at the level of diverse brain structures...