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Silvia N. Calderon

2 papers in the library · 14 citations · publishing 2018-2022

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Considerations in assessing the abuse potential of psychedelics during drug development

Neuropharmacology November 28, 2022 Steven Galati, Dominic Chiapperino, Silvia N. Calderon et al. 14 citations

The recent increase in clinical research on the potential therapeutic uses of classic psychedelics has prompted the need to revisit the assessment of the abuse potential of these drugs. The term "classic psychedelic" is used in this manuscript to describe serotonergic 5-HT2A agonists that alter perception, cognition, and mood (i.e., psychedelic effects) and that are currently controlled in...

DOI: 10.1016/j.neuropharm.2022.109352 (opens in new tab) Psilocybin Substance abuse Schedule Psychotherapist +1

A regulatory perspective on the evaluation of hallucinogen drugs for human use.

Neuropharmacology November 2018 Silvia N. Calderon, Joshua Hunt, Michael Klein

In recent years, there is renewed interest in the study of various hallucinogens for their potential therapeutic effects. In the United States of America (USA), the abuse potential assessment of a drug is carried out as part of the general safety and efficacy evaluation of a drug. Additionally, the abuse potential assessment is taken under consideration in determining if a drug needs to be...

DOI: 10.1016/j.neuropharm.2017.11.028 (opens in new tab) Full text (opens in new tab) Abuse potential hallucinogens Controlled hallucinogens Hallucinogens regulations