Short- and long-term reconfiguration of rat prefrontal cortical networks following single doses of psilocybin
bioRxiv (Cold Spring Harbor Laboratory) December 13, 2024 Ross J. Purple, Rekha Gupta, Christopher W. Thomas et al. 1 citation preprint
SUMMARY We quantify cellular- and circuit-resolution neural network dynamics following therapeutically relevant doses of the psychedelic psilocybin. Using chronically implanted Neuropixels probes, we recorded local field potentials (LFP) alongside action potentials from hundreds of neurons spanning infralimbic, prelimbic and cingulate subregions of the medial prefrontal cortex of...