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Marcos Sintes-Rodriguez

1 paper in the library · 6 citations · publishing 2020

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Psilocybin rescues sociability deficits in an animal model of autism

bioRxiv (Cold Spring Harbor Laboratory) September 10, 2020 Irene Mollinedo-Gajate, Chenchen Song, Marcos Sintes-Rodriguez et al. 6 citations preprint

Abstract Autism spectrum disorder (ASD) is characterized by core deficits in social interaction. The classic serotonergic psychedelic psilocybin has been suggested as a therapeutic agent that may ameliorate in the core symptomology of ASD. We found that the acute response to psilocybin was attenuated in the prenatal valproic acid exposure mouse model of ASD, and importantly, psilocybin rescued...