Anna Skovgaard Lerche

2 papers in the library · 2 citations · publishing 2024-2026

Papers

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Are psychedelics anti-inflammatory? A systematic review and meta-analysis of studies examining the immunomodulatory effects of serotonergic psychedelics.

Brain, Behavior, and Immunity September 28, 2026 Anna Skovgaard Lerche, Dennis Parker Kelley, Michael E Benros et al.

Serotonergic psychedelics are promising treatments for neuropsychiatric disorders, and their immunomodulatory effects may contribute to their clinical efficacy. However, we lack a systematic review and meta-analysis of these effects across in vitro, in vivo non-human, and human studies. We systematically searched PubMed, EMBASE, Web of Science, PsycINFO, LILACS and ClinicalTrials.gov for all...

DOI: 10.1016/j.bbi.2026.107033 Full text 5-ht2ar Inflammation Meta-analysis Serotonergic psychedelics +1

A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy?

Psychedelic Medicine February 28, 2024 Joshua Woolley, Amanda E. Downey, Ellen Bradley et al. 2 citations

Balancing the need for effective treatments against the potential for serious adverse events in those undergoing psilocybin therapy with a family history of BD, we argue for caution in psychedelic clinical trials but not outright exclusion of these individuals. Our risk stratification tool allows for more nuanced inclusion and exclusion criteria.

DOI: 10.1089/psymed.2023.0051 Full text Psilocybin Bipolar disorder Plea Psychotherapist +2