Are psychedelics anti-inflammatory? A systematic review and meta-analysis of studies examining the immunomodulatory effects of serotonergic psychedelics.
Brain, Behavior, and Immunity September 28, 2026 Anna Skovgaard Lerche, Dennis Parker Kelley, Michael E Benros et al.
Serotonergic psychedelics are promising treatments for neuropsychiatric disorders, and their immunomodulatory effects may contribute to their clinical efficacy. However, we lack a systematic review and meta-analysis of these effects across in vitro, in vivo non-human, and human studies. We systematically searched PubMed, EMBASE, Web of Science, PsycINFO, LILACS and ClinicalTrials.gov for all...
DOI: 10.1016/j.bbi.2026.107033 (opens in new tab)
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5-ht2ar
Inflammation
Meta-analysis
Serotonergic psychedelics
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