Daniel A. N. Barbosa

UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice.

Neuropsychopharmacology November 1, 2023 Daniel Ryskamp Rijsketic, Austen B Casey, Daniel A. N. Barbosa et al. 49 citations

The effects of context on the subjective experience of serotonergic psychedelics have not been fully examined in human neuroimaging studies, partly due to limitations of the imaging environment. Here, we administered saline or psilocybin to mice in their home cage or an enriched environment, immunofluorescently-labeled brain-wide c-Fos, and imaged iDISCO+ cleared tissue with light sheet...