Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats
Translational Psychiatry December 14, 2023 Ivan Skorodumov, Rainer Spanagel, Jonathan R Reinwald et al. 25 citations
Abstract Alcohol Use Disorder (AUD) adversely affects the lives of millions of people, but still lacks effective treatment options. Recent advancements in psychedelic research suggest psilocybin to be potentially efficacious for AUD. However, major knowledge gaps remain regarding (1) psilocybin’s general mode of action and (2) AUD-specific alterations of responsivity to psilocybin treatment in...