Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response
Biomedicine & Pharmacotherapy August 29, 2022 Ines Erkizia-Santamaría, R. Alles-Pascual, Igor Horrillo et al. 108 citations
The psychedelic 5-HT2A receptor (5HT2AR) agonist psilocybin (or the active metabolite psilocin) has emerged as potential useful drug for various neuropsychiatric diseases, with a rapid onset of therapeutic activity. However, the mechanisms responsible for such effects remain incompletely characterized. We aimed to study in vitro pharmacological profile and in vivo acute mechanism of...
DOI: 10.1016/j.biopha.2022.113612 (opens in new tab)
Psilocybin
Serotonin
Pharmacology
Hallucinogen
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