Ketamine and its enantiomer esketamine are NMDA receptor antagonists that have shown consistent antidepressant effects in major depression disorder (MDD). These effects suggest an active role of glutamate in the pathophysiology of depression. It has been hypothesized that acute increase of glutamate neurotransmission in the prefrontal cortex following treatment with (es)ketamine leads to...
In this paper, we address a neural field equation that characterizes spatio-temporal propagation of a neural population pulse. Due that the human brain is a complex system whose constituents interaction give rise to fundamental states of consciousness and behavior, it is crucial to gain insight into its functioning even at relativistic scales. To this end, we study the action of the...