Allen d. Radant

Psychedelic Effects of Ketamine in Healthy Volunteers

Anesthesiology 1998 Andrew t. Bowdle, Allen d. Radant, Deborah s. Cowley et al. 371 citations

Background Ketamine has been associated with a unique spectrum of subjective "psychedelic" effects in patients emerging from anesthesia. This study quantified these effects of ketamine and related them to steady-state plasma concentrations. Methods Ketamine or saline was administered in a single-blinded crossover protocol to 10 psychiatrically healthy volunteers using computer-assisted...