Psychedelic Effects of Ketamine in Healthy Volunteers
Anesthesiology 1998 Andrew t. Bowdle, Allen d. Radant, Deborah s. Cowley et al. 371 citations
Background Ketamine has been associated with a unique spectrum of subjective "psychedelic" effects in patients emerging from anesthesia. This study quantified these effects of ketamine and related them to steady-state plasma concentrations. Methods Ketamine or saline was administered in a single-blinded crossover protocol to 10 psychiatrically healthy volunteers using computer-assisted...