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Lawrence P Carter

3 papers in the library · 136 citations · publishing 2012-2013

Papers

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Acute cognitive effects of high doses of dextromethorphan relative to triazolam in humans.

Drug and Alcohol Dependence March 1, 2013 Lawrence P Carter, Chad J Reissig, Matthew W Johnson et al. 28 citations

Although concerns surrounding high-dose dextromethorphan (DXM) abuse have recently increased, few studies have examined the acute cognitive effects of high doses of DXM. The aim of this study was to compare the cognitive effects of DXM with those of triazolam and placebo. Single, acute, oral doses of DXM (100, 200, 300, 400, 500, 600, 700, 800 mg/70 kg), triazolam (0.25, 0.5mg/70 kg), and...

DOI: 10.1016/j.drugalcdep.2012.08.025 (opens in new tab) Full text (opens in new tab) Dextromethorphan Cough suppressant Antitussive Otc medication +19

Cognitive effects of intramuscular ketamine and oral triazolam in healthy volunteers.

Psychopharmacology March 1, 2013 Lawrence P Carter, Bethea A Kleykamp, Roland R. Griffiths et al. 19 citations

Several studies have documented impairments in memory processes as a result of ketamine administration; however, few studies have compared the profile of cognitive effects of ketamine to other drugs. The aim of this study was to compare the cognitive effects of ketamine with those of triazolam in healthy volunteers. Doses of ketamine (0.2, 0.4 mg/kg intramuscular (i.m.)), triazolam (0.2, 0.4...

DOI: 10.1007/s00213-012-2883-x (opens in new tab) Full text (opens in new tab) Cognitive impairment Memory impairment Cognitive dysfunction Mental decline +28

High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens.

Psychopharmacology September 1, 2012 Chad J Reissig, Lawrence P Carter, Matthew W Johnson et al. 89 citations

Although reports of dextromethorphan (DXM) abuse have increased recently, few studies have examined the effects of high doses of DXM. This study in humans evaluated the effects of supratherapeutic doses of DXM and triazolam. Single, acute oral doses of DXM (100, 200, 300, 400, 500, 600, 700, and 800 mg/70 kg), triazolam (0.25 and 0.5 mg/70 kg), and placebo were administered to 12 healthy...

DOI: 10.1007/s00213-012-2680-6 (opens in new tab) Full text (opens in new tab) Dxm Dextromethorphan Cough suppressant Psychedelic experience +12