Neuropharmacology
April 3, 2014
David Martin, Danuta Marona‐lewicka, D. E. Nichols et al.
Chronic administration of lysergic acid diethylamide (LSD) every other day to rats results in a variety of abnormal behaviors. These build over the 90 day course of treatment and can persist at full strength for at least several months after cessation of treatment. The behaviors are consistent with those observed in animal models of schizophrenia and include hyperactivity, reduced...
ChemInform
January 6, 1998
Aaron Monte, Steve R. Waldman, Danuta Marona‐lewicka et al.
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Journal of Medicinal Chemistry
September 1, 1995
Robert Oberlender, P. V. Ramachandran, Michael P. Johnson et al.
8 citations
The potency of hallucinogenic amphetamine derivatives of the 1-(2,5-dimethoxy-4-alkylphenyl)-2-aminopropane type drops dramatically when the length of the 4-alkyl substituent exceeds propyl or when the substituent is branched. This investigation was directed toward evaluating changes in behavioral and biochemical pharmacology resulting from introducing chirality into the 4-alkyl group of such...
Chemischer Informationsdienst
June 10, 1986
D. E. Nichols, Andrew J. Hoffman, Robert Oberlender et al.
AbstractDie aus den Dihydrobenzofuranen (I) zugänglichen Aldehyde (II) werden durch Kondensation mit Nitroethan und anschließende Reduktion in die Aminopropyl‐Derivate (V) übergeführt, die auf LSD‐analoge Wirkung bei Ratten geprüft werden.
Chemischer Informationsdienst
July 5, 1977
D. E. Nichols, Donald C. Dyer
Abstract2,6‐Dimethoxy‐phenol (I) liefert die Phenylacetonitrile (II), die zu (III) alkyliert und dann zu den Phenäthylaminen (IV) reduziert werden.