Numerous mental illnesses have been connected to the dysregulation of particular brain systems. However, few therapy approaches are able to change such specific patterns of brain activity. Nevertheless, this may be accomplished using closed-loop brain imaging techniques like neurofeedback, which aim to directly alter brain activity. Yet, due to methodological issues and the lack of specificity...
Adolescents experience alarmingly high rates of major depressive disorder (MDD), however, gold-standard treatments are only effective for ~50% of youth. Accordingly, there is a critical need to develop novel interventions, particularly ones that target neural mechanisms believed to potentiate depressive symptoms. Directly addressing this gap, we developed mindfulness-based fMRI neurofeedback...