The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules.
Cell Reports July 23, 2024 Kexin Jiang, You Zheng, Liting Zeng et al. 12 citations
Increasing global concerns about psychoactive substance addiction and psychotic disorders highlight the need for comprehensive research into the structure-function relationship governing ligand recognition between these substances and their receptors in the brain. Recent studies indicate the significant involvement of trace amine-associated receptor 1 (TAAR1) in the signaling regulation of the...