Lysergic acid diethylamide induces behavioral changes in Caenorhabditis elegans.
Neuroscience Letters August 10, 2024 Isis M. Ornelas, Beatriz de S. Carrilho, Matheus Antonio V. de C. Ventura et al. 3 citations
Lysergic acid diethylamide (LSD) is a synthetic psychedelic compound with potential therapeutic value for psychiatric disorders. This study aims to establish Caenorhabditis elegans as an in vivo model for examining LSD's effects on locomotor behavior. Our results demonstrate that LSD is absorbed by C. elegans and that the acute treatment reduces animal speed, similar to the role of endogenous...