Ruth H Asch

Challenges and rewards of in vivo synaptic density imaging, and its application to the study of depression.

Neuropsychopharmacology November 1, 2024 Ruth H Asch, Chadi G. Abdallah, Richard E. Carson et al. 11 citations

The development of novel radiotracers for Positron Emission Tomography (PET) imaging agents targeting the synaptic vesicle glycoprotein 2 A (SV2A), an integral glycoprotein present in the membrane of all synaptic vesicles throughout the central nervous system, provides a method for the in vivo quantification of synaptic density. This is of particular interest in neuropsychiatric disorders given...