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Laura K Milton

3 papers in the library · 16 citations · publishing 2024-2026

Papers

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Appetite for change: How psilocybin reshapes food reward learning through striatal dopamine function

bioRxiv May 18, 2026 Kyna Conn, Ngok Wong, Serenay Sunnetci et al.

Abstract Psilocybin has emerged as a promising therapeutic agent for psychiatric disorders characterised by cognitive rigidity and disrupted reward processing, including anorexia nervosa. While its pro-cognitive effects have been mechanistically probed almost exclusively through serotonin receptor subtype antagonism, the downstream contributions of dopaminergic systems to these outcomes remain...

Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats.

Translational Psychiatry September 30, 2024 Elizabeth L. Fisher, Ryan Smith, Kyna Conn et al. 14 citations

Psilocybin has shown promise as a novel pharmacological intervention for treatment of depression, where post-acute effects of psilocybin treatment have been associated with increased positive mood and decreased pessimism. Although psilocybin is proving to be effective in clinical trials for treatment of psychiatric disorders, the information processing mechanisms affected by psilocybin are not...

Psilocybin increases optimistic engagement over time: computational modelling of behavior in rats

bioRxiv (Cold Spring Harbor Laboratory) May 17, 2024 Elizabeth L. Fisher, Ryan Smith, Andrew W. Corcoran et al. 2 citations preprint

Abstract Psilocybin has shown promise as a novel pharmacological intervention for treatment of depression, where post-acute effects of psilocybin treatment have been associated with increased positive mood and decreased pessimism. Although psilocybin is proving to be effective in clinical trials for treatment of psychiatric disorders, the information processing mechanisms affected by psilocybin...