Nightmares are a common symptom in narcolepsy that has not been targeted in prior clinical trials. This study investigated the efficacy of Cognitive Behavioural Therapy for Nightmares (CBT-N), adapted for narcolepsy, in a small group of adults. Given the high prevalence of lucid dreaming in narcolepsy, we added a promising adjuvant component, targeted lucidity reactivation (TLR), a procedure...
Abstract Introduction Limited information is available to quantify hypnagogic/hypnopompic hallucination (HH) events people with narcolepsy (PWN) may experience. This post hoc analysis from the phase 3 REST-ON trial evaluated individual HH types. Methods REST-ON (NCT02720744) participants (age ≥16 years) with narcolepsy were randomized 1:1 to once-nightly sodium oxybate (ON-SXB) (week 1, 4.5 g;...
Mindfulness-based interventions (MBI) have been shown to improve psychosocial functioning in medical populations but have not been studied in narcolepsy. This study examined the feasibility and acceptability of an MBI that was adapted for narcolepsy, including three variations in program length. Adults with narcolepsy (N = 60) were randomized to MBI groups of varying durations: brief (4 weeks),...