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Milan Van Maldegem

2 papers in the library · 5 citations · publishing 2024-2025

Papers

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Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness.

British Journal of Anaesthesia April 1, 2025 Milan Van Maldegem, Jakub Vohryzek, Selen Atasoy et al. 3 citations

Ketamine, in doses suitable to induce anaesthesia in humans, gives rise to a unique state of unresponsiveness accompanied by vivid experiences and sensations, making it possible to disentangle the correlated but distinct concepts of conscious awareness and behavioural responsiveness. This distinction is often overlooked in the study of consciousness. The mathematical framework of connectome...

Ketamine-Induced Unresponsiveness Shows a Harmonic Shift from Global to Localised Functional Organisation

bioRxiv (Cold Spring Harbor Laboratory) June 25, 2024 Milan Van Maldegem, Jakub Vohryzek, Selen Atasoy et al. 2 citations preprint

Abstract Ketamine is classified as a dissociative anaesthetic that, in sub-anaesthetic doses, can produce an altered state of consciousness characterised by dissociative symptoms, visual and auditory hallucinations, and perceptual distortions. Given the anaesthetic-like and psychedelic-like nature of this compound, it is expected to have different effects on brain dynamics in anaesthetic doses...