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Joon-Hyuk Lee

3 papers in the library · publishing 2023-2025

Papers

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Mediodorsal thalamic nucleus mediates resistance to ethanol through Cav3.1 T-type Ca2+ regulation of neural activity.

Elife July 18, 2025 Charles-Francois V Latchoumane, Joon-Hyuk Lee, Seong-Wook Kim et al.

Thalamocortical activity is known to orchestrate sensory gating and consciousness switching. The precise thalamic regions involved, or the firing patterns related to the unconsciousness, remain unclear. Interestingly, the highly -expressed thalamic T-type calcium currents have been considered as a candidate for the ionic mechanism for the generation of thalamocortically driven change in...

Psychedelic control of neuroimmune interactions governing fear

Nature April 23, 2025 Elizabeth N. Chung, Jinsu Lee, C. Polonio et al.

Neuroimmune interactions—signals transmitted between immune and brain cells—regulate many aspects of tissue physiology1, including responses to psychological stress2, 3, 4–5, which can predispose individuals to develop neuropsychiatric diseases6, 7, 8–9. Still, the interactions between haematopoietic and brain-resident cells that influence complex behaviours are poorly understood. Here, we use...

Mediodorsal thalamic nucleus mediates resistance to ethanol through Cav3.1 T-type Ca 2+ regulation of neural activity

bioRxiv September 27, 2023 Charles-Francois V Latchoumane, Joon-Hyuk Lee, Seong-Wook Kim et al. preprint

ABSTRACT: Thalamocortical activity is known to orchestrate sensory gating and consciousness switching. The precise thalamic regions involved, or the firing patterns related to the unconsciousness remain unclear. Interestingly, the highly-expressed thalamic T-type calcium currents have been considered as a candidate for the ionic mechanism for the generation of thalamo-cortically-driven change...