Acta crystallographica. Section E, Crystallographic communications
March 1, 2025
Ryan E Mewis, Matthew C Hulme, Jack Marron et al.
Diphenidine (1a), a dissociative anaesthetic, was first reported in 2013. Since then, a number of derivatives e.g. 2-methoxphenidine (1b) have been produced by clandestine laboratories and sold as research chemicals. Fluorinated diphenidines, namely, [1-(2,6-di-fluoro-phen-yl)-2-phenyl-eth-yl]di-methyl-aza-nium chloride, C16H18F2N+·Cl-, (I),...
Journal of Pharmaceutical and Biomedical Analysis
July 15, 2022
Jennifer K Field, Christine Hinz, Christopher M Titman et al.
4 citations
This study describes the first reported development of a rapid, generic gradient Ultra-High Performance Liquid Chromatography (UHPLC) methodology with targeted triple quadrupole MS/MS using electrospray positive ionisation to detect and unambiguously confirm the identity of 33 substituted 1, 2-diarylethamine (or diphenidine) derivatives in solid drug samples. The in-house synthesised library...
ACS Omega
August 29, 2019
H. Elbardisy, Christopher W. Foster, Jack Marron et al.
The emergence of a new class of novel psychoactive substances, N-benzyl-substituted phenethylamine derivatives so-called “NBOMes” or “Smiles”, in the recreational drug market has forced the development of new sensitive analytical methodologies for their detection and quantitation. NBOMes’ hallucinogenic effects mimic those of the illegal psychedelic drug lysergic acid diethylamide (LSD) and are...
Analytical and Bioanalytical Chemistry
November 1, 2016
Pierre M Geyer, Matthew C Hulme, Joseph P B Irving et al.
The prevalence of new psychoactive substances (NPSs) in forensic casework has increased prominently in recent years. This has given rise to significant legal and analytical challenges in the identification of these substances. The requirement for validated, robust and rapid testing methodologies for these compounds is obvious. This study details the analysis of 13 synthesised diphenidine...