Robert J Lee

2 papers in the library · 4 citations · publishing 2016-2022

Papers

Guilty by dissociation: Part A: Development of a rapid Ultra-High Performance Liquid Chromatography (UHPLC)-MS/MS methodology for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS).

Journal of Pharmaceutical and Biomedical Analysis July 15, 2022 Jennifer K Field, Christine Hinz, Christopher M Titman et al. 4 citations

A rapid UHPLC-MS/MS method can detect and confirm 33 different diphenidine derivatives in solid drug samples. The method separates compounds based on the position and type of chemical substituents on the phenyl ring, and it works even when common adulterants are present. The 10-minute protocol was successfully used to identify psychoactive components in four seized drug samples from law enforcement.

DOI: 10.1016/j.jpba.2022.114798 Full text Diphenidines Forensic Illicit drugs Novel psychoactive substances +2

Guilty by dissociation-development of gas chromatography-mass spectrometry (GC-MS) and other rapid screening methods for the analysis of 13 diphenidine-derived new psychoactive substances (NPSs).

Analytical and Bioanalytical Chemistry November 1, 2016 Pierre M Geyer, Matthew C Hulme, Joseph P B Irving et al.

A validated gas chromatography-mass spectrometry (GC-MS) method provides both screening and quantification of 13 diphenidine derivatives in seized solid samples, whether pure or mixed with common adulterants. The work addresses the rising forensic and analytical challenges posed by new psychoactive substances (NPSs) by offering a rapid, robust testing methodology. Techniques include presumptive testing, thin layer chromatography, and GC-MS, with the latter offering first-time general screening and quantification for these compounds in casework.

DOI: 10.1007/s00216-016-9969-y Full text Characterisation nmr, ft-ir Diphenidine Gc–ms Methoxphenidine +2