arXiv Preprint Archive
May 26, 2014
Enzo Tagliazucchi, Robin Carhart-Harris, Robert Leech et al.
The study of rapid changes in brain dynamics and functional connectivity (FC) is of increasing interest in neuroimaging. Brain states departing from normal waking consciousness are expected to be accompanied by alterations in the aforementioned dynamics. In particular, the psychedelic experience produced by psilocybin (a substance found in `magic mushrooms`) is characterized by unconstrained...
Frontiers in Human Neuroscience
2014
Robin Carhart-Harris, Robert Leech, Peter J. Hellyer et al.
1,289 citations
Entropy is a dimensionless quantity that is used for measuring uncertainty about the state of a system but it can also imply physical qualities, where high entropy is synonymous with high disorder. Entropy is applied here in the context of states of consciousness and their associated neurodynamics, with a particular focus on the psychedelic state. The psychedelic state is considered an exemplar...
Proceedings of the National Academy of Sciences
September 3, 2013
Enzo Tagliazucchi, Frederic von Wegner, Astrid Morzelewski et al.
278 citations
The integration of segregated brain functional modules is a prerequisite for conscious awareness during wakeful rest. Here, we test the hypothesis that temporal integration, measured as long-term memory in the history of neural activity, is another important quality underlying conscious awareness. For this aim, we study the temporal memory of blood oxygen level-dependent signals across the...
Frontiers in Psychology
2013
Enzo Tagliazucchi, Marion Behrens, Helmut Laufs
42 citations
Human deep sleep is characterized by reduced sensory activity, responsiveness to stimuli, and conscious awareness. Given its ubiquity and reversible nature, it represents an attractive paradigm to study the neural changes which accompany the loss of consciousness in humans. In particular, the deepest stages of sleep can serve as an empirical test for the predictions of theoretical models...
Preprints.org
Enzo Tagliazucchi
2 citations
preprint
Serotonergic psychedelics are known to elicit changes in conscious awareness, including perception of the environment and the self, as well as in mood, emotion and different aspects of cognition (Nichols, 2016). The effect of these compounds is complex and resists a straightforward classification that is useful for other drugs, such as “stimulants” or “sedatives”. While the effects of certain...