Intracellular studies on the effects of systemic administration of serotonin agonists on rat facial motoneurons.
European Journal of Pharmacology February 26, 1982 C P Vandermaelen, G K Aghajanian 37 citations
Intracellular recordings were made from facial motoneurons of anesthetized rats during systemic administration of 5-methoxy-N,-N-dimethyltryptamine (5-MeODMT) and p-chloroamphetamine (PCA), drugs which elicit the behavioral serotonin syndrome. Both drugs caused a slow depolarization, increased input resistance, and increased excitability of facial motoneurons. These changes are identical to...